FACS analysis of mouse C57Bl/6 splenocytes using GTX01473-02 IL7 Receptor alpha antibody [A7R34] (Biotin). Right panel : co-stained with IL7 Receptor alpha antibody [A7R34] (Biotin) and Mouse CD3 antibody (APC) Left panel : co-stained with isotype control and Mouse CD3 antibody (APC) antibody amount : 0.06 microg (5 microl)
FACS analysis of mouse C57Bl/6 splenocytes using GTX01473-02 IL7 Receptor alpha antibody [A7R34] (Biotin). Right panel : co-stained with IL7 Receptor alpha antibody [A7R34] (Biotin) and Mouse CD3 antibody (APC) Left panel : co-stained with isotype control and Mouse CD3 antibody (APC) antibody amount : 0.06 microg (5 microl)
IL7 Receptor alpha antibody [A7R34] (Biotin)
GTX01473-02
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Mouse
TargetIl7r
Overview
- SupplierGeneTex
- Product NameIL7 Receptor alpha antibody [A7R34] (Biotin)
- Delivery Days Customer9
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDA7R34
- Concentration0.5 mg/ml
- ConjugateBiotin
- Gene ID16197
- Target nameIl7r
- Target descriptioninterleukin 7 receptor
- Target synonymsCD127; IL-; IL-7 receptor alpha chain; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7RA; IL-7Ralpha; IL-7R-alpha; interleukin 7 receptor alpha chain; interleukin-7 receptor subunit alpha
- HostRat
- IsotypeIgG2a
- Scientific DescriptionInterleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles. Alshekaili J et al., 2018 Feb 23, Sci RepRead more
- Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell. Thaventhiran JE et al., 2012 Aug 14, Proc Natl Acad Sci U S ARead more
- In vivo administration of the recombinant IL-7/hepatocyte growth factor beta hybrid cytokine efficiently restores thymopoiesis and naive T cell generation in lethally irradiated mice after syngeneic bone marrow transplantation. Jin J et al., 2011 Feb 15, J ImmunolRead more
- LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. Vondenhoff MF et al., 2009 May 1, J ImmunolRead more
- Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis. Leithaeuser F et al., 2006 Jun, Am J PatholRead more
- TCR signals mediated by Src family kinases are essential for the survival of naive T cells. Seddon B et al., 2002 Sep 15, J ImmunolRead more
- Expression and function of the interleukin 7 receptor in murine lymphocytes. Sudo T et al., 1993 Oct 1, Proc Natl Acad Sci U S ARead more