iLite® G-CSF*

Svar Life Science

iLite® G-CSF*

9

Assay Ready Cells

Research Use Only

The iLite® G-CSF Assay Ready Cells offers a cell-based assay that enables the study and targeting of the G-CSF and it ́s receptor with the advantage of a biologically relevant assay system giving both a functional and quantitative read-out. The iLite® G-CSF assay ready cells enable a broad usage throughout this development with applications such as functional screening, functional characterization, QC lot release (potency) assays and neutralizing antibody studies. The assay ready iLite® G-CSF cells are avian DT-40 cells (ATCC#CRL2111) which have been genetically engineered to be responsive to G-CSF, resulting in the specific expression of Firefly Luciferase. Normalization of cell counts and serum matrix effects is obtained by a second reporter gene, a Renilla Luciferase reporter gene construct, under control of a constitutive promotor. The ATCC® CRL-2111 cell line is used under a license from ATCC®

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