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ProductsBack/ING3 Polyclonal Antibody

Western blot analysis of extracts of various cell lines using ING3 Polyclonal Antibody at 1:1000 dilution.

Western blot analysis of extracts of various cell lines using ING3 Polyclonal Antibody at 1:1000 dilution.

Western blot analysis of extracts of various cell lines using ING3 Polyclonal Antibody at 1:1000 dilution.

ING3 Polyclonal Antibody

E-AB-61140

Product group Antibodies

Overview

Supplier
Elabscience
Product Name
ING3 Polyclonal Antibody
Delivery Days Customer
12
Certification
Research Use Only
Scientific Description
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
UNSPSC
12352203

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