![IHC-P analysis of human pancreatic neuroendocrine tumor (PNET, insulinoma) tissue using GTX639932 Insulin antibody [HMV308] HistoMAX?. Strong Insulin positivity of most tumor cells. IHC-P analysis of human pancreatic neuroendocrine tumor (PNET, insulinoma) tissue using GTX639932 Insulin antibody [HMV308] HistoMAX?. Strong Insulin positivity of most tumor cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639932/GTX639932_20240312_IHC-P_1_24031120_732.webp)
IHC-P analysis of human pancreatic neuroendocrine tumor (PNET, insulinoma) tissue using GTX639932 Insulin antibody [HMV308] HistoMAX?. Strong Insulin positivity of most tumor cells.
Insulin antibody [HMV308] HistoMAX(tm)
GTX639932
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetINS
Overview
- SupplierGeneTex
- Product NameInsulin antibody [HMV308] HistoMAX(tm)
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHMV308
- Concentration8 ug/ml
- ConjugateUnconjugated
- Gene ID3630
- Target nameINS
- Target descriptioninsulin
- Target synonymsIDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10, PNDM4, insulin, preproinsulin, proinsulin
- HostRabbit
- IsotypeIgG
- Protein IDP01308
- Protein NameInsulin
- Scientific DescriptionAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
![IHC-P analysis of human pancreas tissue using GTX639932 Insulin antibody [HMV308] HistoMAX?. Pancreas with a strong cytoplasmic insulin staining of the majority of islet cells. IHC-P analysis of human pancreas tissue using GTX639932 Insulin antibody [HMV308] HistoMAX?. Pancreas with a strong cytoplasmic insulin staining of the majority of islet cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639932/GTX639932_20240312_IHC-P_24031120_708.webp)
![IHC-P analysis of human colon tissue using GTX639932 Insulin antibody [HMV308] HistoMAX?. Colon sample completely lacking insulin staining. IHC-P analysis of human colon tissue using GTX639932 Insulin antibody [HMV308] HistoMAX?. Colon sample completely lacking insulin staining.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639932/GTX639932_20240312_IHC-P_2_24031120_798.webp)




![Mouse tissue extract (50 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with Insulin antibody [GT1229] (GTX02826) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX02826/GTX02826_4000000209_20210122_WB_M_pancreas_w_23053123_391.webp)

![An ELISA plate is coated with 50 μL of a Proinsulin recombinant protein at concentration ranged from 0.2 μg/mL to 1.6 μg/mL. The coated protein is detected with anti-C-peptide antibody [GT1489] (GTX631942) at 500 ng/mL.](https://www.genetex.com/upload/website/prouct_img/normal/GTX631942/GTX631942_41848_20150206_ELISA_w_23061202_525.webp)
![An ELISA plate is coated with 50 μL of a Proinsulin recombinant protein at concentration ranged from 0.2 μg/mL to 1.6 μg/mL. The coated protein is detected with anti-C-peptide antibody [GT1519] (GTX631943) at 500 ng/mL.](https://www.genetex.com/upload/website/prouct_img/normal/GTX631943/GTX631943_41848_20150206_ELISA_w_23061202_907.webp)