IHC-P analysis of human placenta tissue section using GTX02652 Insulin Receptor alpha antibody [INSR/2277R].
IHC-P analysis of human placenta tissue section using GTX02652 Insulin Receptor alpha antibody [INSR/2277R].
Insulin Receptor alpha antibody [INSR/2277R]
GTX02652
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetINSR
Overview
- SupplierGeneTex
- Product NameInsulin Receptor alpha antibody [INSR/2277R]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDINSR/2277R
- Concentration200 ug/ml
- ConjugateUnconjugated
- Gene ID3643
- Target nameINSR
- Target descriptioninsulin receptor
- Target synonymsCD220; HHF5; insulin receptor; IR
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203