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Interferon gamma Receptor 1 antibody

GTX103098
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetIFNGR1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Interferon gamma Receptor 1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3459
  • Target name
    IFNGR1
  • Target description
    interferon gamma receptor 1
  • Target synonyms
    CD119, IFNGR, IMD27A, IMD27B, interferon gamma receptor 1, AVP, type 2, CD119 antigen, CDw119, IFN-gamma receptor 1, IFN-gamma-R-alpha, IFN-gamma-R1, antiviral protein, type 2, immune interferon receptor 1, interferon-gamma receptor alpha chain
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP15260
  • Protein Name
    Interferon gamma receptor 1
  • Scientific Description
    This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Kim DY, Lim SG, Suk K, et al. Mitochondrial dysfunction regulates the JAK-STAT pathway via LKB1-mediated AMPK activation ER-stress-independent manner. Biochem Cell Biol. 2020,98(2):137-144. doi: 10.1139/bcb-2019-0088
    Read this paper
  • Matsuzawa T, Kim BH, Shenoy AR, et al. IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway. J Immunol. 2012,189(2):813-8. doi: 10.4049/jimmunol.1102041
    Read this paper