INTS6 Antibody, FITC conjugated

Cusabio

INTS6 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

INTS6

integrator complex subunit 6

DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2, integrator complex subunit 6, DEAD box protein, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26, RNA helicase HDB, protein deleted in cancer 1

Rabbit

IgG

Integrator complex subunit 6

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).

Human

-20°C or -80°C

41116161