InVivoMAb anti-human CD47

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity. Gordon SR et al., 2017 May 25, Nature

Anti-CD47 antibody suppresses tumour growth and augments the effect of chemotherapy treatment in hepatocellular carcinoma. Lo J et al., 2016 May, Liver Int

Nuclear factor kappa B-mediated CD47 up-regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice. Lo J et al., 2015 Aug, Hepatology

Antibody mediated therapy targeting CD47 inhibits tumor progression of hepatocellular carcinoma. Xiao Z et al., 2015 May 1, Cancer Lett

Blockade of CD47-mediated cathepsin S/protease-activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma. Lee TK et al., 2014 Jul, Hepatology

Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response. Tseng D et al., 2013 Jul 2, Proc Natl Acad Sci U S A