Bio-Connect

InVivoMAb anti-rat CD47

BE0446
Bio X Cell
ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Product group Antibodies
ReactivityRat
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-rat CD47
  • Delivery Days Customer
    7
  • Applications
    Functional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    OX-101
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    ≥95% , Determined by SDS-PAGE
  • Host
    Mouse
  • Isotype
    IgG1
  • Reactivity
    Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116161

References

  • CD47 blocking antibody accelerates hematoma clearance and alleviates hydrocephalus after experimental intraventricular hemorrhage.
    Read this paper
  • TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction.
    Read this paper
  • CD47 blockade reduces ischemia-reperfusion injury and improves outcomes in a rat kidney transplant model.
    Read this paper
  • Cardiac CD47 drives left ventricular heart failure through Ca2+-CaMKII-regulated induction of HDAC3.
    Read this paper
  • Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1.
    Read this paper
  • Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.
    Read this paper
  • Thrombospondin-1/CD47 blockade following ischemia-reperfusion injury is tissue protective.
    Read this paper
  • Activation of CD47 receptors causes histamine secretion from mast cells.
    Read this paper
  • Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways.
    Read this paper
  • Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endothelium.
    Read this paper