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InVivoMAb anti-rat CD47

BE0446
Bio X Cell
ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Product group Antibodies
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-rat CD47
  • Delivery Days Customer
    7
  • Applications
    Functional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    OX-101
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Mouse
  • Isotype
    IgG1
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Ye F, Hua Y, Keep RF, et al. CD47 blocking antibody accelerates hematoma clearance and alleviates hydrocephalus after experimental intraventricular hemorrhage. Neurobiol Dis. 2021,155:105384. doi: 10.1016/j.nbd.2021.105384
    Read this paper
  • Rogers NM, Sharifi-Sanjani M, Yao M, et al. TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction. Cardiovasc Res. 2017,113(1):15-29. doi: 10.1093/cvr/cvw218
    Read this paper
  • Lin Y, Manning PT, Jia J, et al. CD47 blockade reduces ischemia-reperfusion injury and improves outcomes in a rat kidney transplant model. Transplantation. 2014,98(4):394-401. doi: 10.1097/TP.0000000000000252
    Read this paper
  • Sharifi-Sanjani M, Shoushtari AH, Quiroz M, et al. Cardiac CD47 drives left ventricular heart failure through Ca2+-CaMKII-regulated induction of HDAC3. J Am Heart Assoc. 2014,3(3):e000670. doi: 10.1161/JAHA.113.000670
    Read this paper
  • Csányi G, Yao M, Rodríguez AI, et al. Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1. Arterioscler Thromb Vasc Biol. 2012,32(12):2966-73. doi: 10.1161/ATVBAHA.112.300031
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  • Bauer PM, Bauer EM, Rogers NM, et al. Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1. Cardiovasc Res. 2012,93(4):682-93. doi: 10.1093/cvr/cvr356
    Read this paper
  • Maxhimer JB, Shih HB, Isenberg JS, et al. Thrombospondin-1/CD47 blockade following ischemia-reperfusion injury is tissue protective. Plast Reconstr Surg. 2009,124(6):1880-1889. doi: 10.1097/PRS.0b013e3181bceec3
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  • Sick E, Niederhoffer N, Takeda K, et al. Activation of CD47 receptors causes histamine secretion from mast cells. Cell Mol Life Sci. 2009,66(7):1271-82. doi: 10.1007/s00018-009-8778-2
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  • Alblas J, Honing H, de Lavalette CR, et al. Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways. Mol Cell Biol. 2005,25(16):7181-92.
    Read this paper
  • de Vries HE, Hendriks JJ, Honing H, et al. Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endothelium. J Immunol. 2002,168(11):5832-9.
    Read this paper