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InVivoMAb anti-mouse CD3epsilon
BE0261
ApplicationsImmunoFluorescence, Other Application
Product group Antibodies
ReactivityMouse
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-mouse CD3epsilon
- Delivery Days Customer7
- ApplicationsImmunoFluorescence, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDKT3
- Concentration4-11 mg/ml
- Estimated Purity>95%
- HostRat
- IsotypeIgG2a
- Scientific DescriptionThe KT3 monoclonal antibody reacts with mouse CD3ε, a 20 kDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. CD3ε is one of five polypeptide chains that combine to form the TCR complex. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays roles in TCR signaling, T lymphocyte activation, and antigen recognition. The KT3 antibody has been shown to induce T lymphocyte activation via binding and stimulating the TCR.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Criteria for dendritic cell receptor selection for efficient antibody-targeted vaccination. Reuter A et al., 2015 Mar 15, J ImmunolRead more
- Lymphoid tissue and plasmacytoid dendritic cells and macrophages do not share a common macrophage-dendritic cell-restricted progenitor. Sathe P et al., 2014 Jul 17, ImmunityRead more
- Gene expression in the Gitr locus is regulated by NF-kappaB and Foxp3 through an enhancer. Tone Y et al., 2014 Apr 15, J ImmunolRead more
- Lung-resident CD4+ T cells are sufficient for IL-4Ralpha-dependent recall immunity to Nippostrongylus brasiliensis infection. Thawer SG et al., 2014 Mar, Mucosal ImmunolRead more
- Hepatitis B virus-like particles access major histocompatibility class I and II antigen presentation pathways in primary dendritic cells. Moffat JM et al., 2013 Apr 26, VaccineRead more
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