InVivoMAb anti-mouse IL-2

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Clouthier DL, Zhou AC, Wortzman ME, et al. GITR intrinsically sustains early type 1 and late follicular helper CD4 T cell accumulation to control a chronic viral infection. PLoS Pathog. 2015,11(1):e1004517. doi: 10.1371/journal.ppat.1004517

Baeyens A, Saadoun D, Billiard F, et al. Effector T cells boost regulatory T cell expansion by IL-2, TNF, OX40, and plasmacytoid dendritic cells depending on the immune context. J Immunol. 2015,194(3):999-1010. doi: 10.4049/jimmunol.1400504

McKinstry KK, Strutt TM, Bautista B, et al. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014,5:5377. doi: 10.1038/ncomms6377

Mizui M, Koga T, Lieberman LA, et al. IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells. J Immunol. 2014,193(5):2168-77. doi: 10.4049/jimmunol.1400977

Srivastava S, Koch MA, Pepper M, et al. Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection. J Exp Med. 2014,211(5):961-74. doi: 10.1084/jem.20131556

Gasteiger G, Hemmers S, Bos PD, et al. IL-2-dependent adaptive control of NK cell homeostasis. J Exp Med. 2013,210(6):1179-87. doi: 10.1084/jem.20122571

Gratz IK, Truong HA, Yang SH, et al. Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues. J Immunol. 2013,190(9):4483-7. doi: 10.4049/jimmunol.1300212

Smith C, Martinez M, Peet J, et al. Differential outcome of IL-2/anti-IL-2 complex therapy on effector and memory CD8+ T cells following vaccination with an adenoviral vector encoding EBV epitopes. J Immunol. 2011,186(10):5784-90. doi: 10.4049/jimmunol.1003394

Hamilton SE, Schenkel JM, Akue AD, et al. IL-2 complex treatment can protect naive mice from bacterial and viral infection. J Immunol. 2010,185(11):6584-90. doi: 10.4049/jimmunol.1001215