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InVivoMAb anti-mouse IL-2

BE0043
Bio X Cell
ApplicationsNeutralisation/Blocking, Other Application
Product group Antibodies
ReactivityMouse
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-mouse IL-2
  • Delivery Days Customer
    7
  • Applications
    Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    JES6-1A12
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Rat
  • Isotype
    IgG2a
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Littwitz-Salomon E, Akhmetzyanova I, Vallet C, et al. Activated regulatory T cells suppress effector NK cell responses by an IL-2-mediated mechanism during an acute retroviral infection. Retrovirology. 2015,12:66. doi: 10.1186/s12977-015-0191-3
    Read this paper
  • Bouchery T, Kyle R, Camberis M, et al. ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms. Nat Commun. 2015,6:6970. doi: 10.1038/ncomms7970
    Read this paper
  • McKinstry KK, Strutt TM, Bautista B, et al. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014,5:5377. doi: 10.1038/ncomms6377
    Read this paper
  • Marshall D, Sinclair C, Tung S, et al. Differential requirement for IL-2 and IL-15 during bifurcated development of thymic regulatory T cells. J Immunol. 2014,193(11):5525-33. doi: 10.4049/jimmunol.1402144
    Read this paper
  • Joedicke JJ, Myers L, Carmody AB, et al. Activated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling. J Immunol. 2014,193(6):2952-60. doi: 10.4049/jimmunol.1400649
    Read this paper
  • Mizui M, Koga T, Lieberman LA, et al. IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells. J Immunol. 2014,193(5):2168-77. doi: 10.4049/jimmunol.1400977
    Read this paper
  • Myers L, Joedicke JJ, Carmody AB, et al. IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection. J Immunol. 2013,190(11):5485-95. doi: 10.4049/jimmunol.1202951
    Read this paper
  • McNally A, Hill GR, Sparwasser T, et al. CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proc Natl Acad Sci U S A. 2011,108(18):7529-34. doi: 10.1073/pnas.1103782108
    Read this paper
  • Le Saout C, Villard M, Cabasse C, et al. IL-2 mediates CD4+ T cell help in the breakdown of memory-like CD8+ T cell tolerance under lymphopenic conditions. PLoS One. 2010,5(9):e12659. doi: 10.1371/journal.pone.0012659
    Read this paper
  • Bihl F, Pecheur J, Bréart B, et al. Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection. J Immunol. 2010,185(4):2174-81. doi: 10.4049/jimmunol.1001486
    Read this paper