InVivoMAb anti-mouse IL-2

Activated regulatory T cells suppress effector NK cell responses by an IL-2-mediated mechanism during an acute retroviral infection. Littwitz-Salomon E et al., 2015 Jul 30, Retrovirology

ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms. Bouchery T et al., 2015 Apr 27, Nat Commun

Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. McKinstry KK et al., 2014 Nov 5, Nat Commun

Differential requirement for IL-2 and IL-15 during bifurcated development of thymic regulatory T cells. Marshall D et al., 2014 Dec 1, J Immunol

Activated CD8+ T cells induce expansion of Vbeta5+ regulatory T cells via TNFR2 signaling. Joedicke JJ et al., 2014 Sep 15, J Immunol

IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells. Mizui M et al., 2014 Sep 1, J Immunol

IL-2-independent and TNF-alpha-dependent expansion of Vbeta5+ natural regulatory T cells during retrovirus infection. Myers L et al., 2013 Jun 1, J Immunol

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. McNally A et al., 2011 May 3, Proc Natl Acad Sci U S A

IL-2 mediates CD4+ T cell help in the breakdown of memory-like CD8+ T cell tolerance under lymphopenic conditions. Le Saout C et al., 2010 Sep 10, PLoS One

Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection. Bihl F et al., 2010 Aug 15, J Immunol