InVivoMAb anti-mouse TIM-1 (CD365)

Yeung MY, Ding Q, Brooks CR, et al. TIM-1 signaling is required for maintenance and induction of regulatory B cells. Am J Transplant. 2015,15(4):942-53. doi: 10.1111/ajt.13087

Lee KM, Stott RT, Zhao G, et al. TGF-β-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance. Eur J Immunol. 2014,44(6):1728-36. doi: 10.1002/eji.201344062

Tan X, Jie Y, Zhang Y, et al. Tim-1 blockade with RMT1-10 increases T regulatory cells and prolongs the survival of high-risk corneal allografts in mice. Exp Eye Res. 2014,122:86-93. doi: 10.1016/j.exer.2014.02.019

Zhang Y, Ji H, Shen X, et al. Targeting TIM-1 on CD4 T cells depresses macrophage activation and overcomes ischemia-reperfusion injury in mouse orthotopic liver transplantation. Am J Transplant. 2013,13(1):56-66. doi: 10.1111/j.1600-6143.2012.04316.x

Ding Q, Yeung M, Camirand G, et al. Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Invest. 2011,121(9):3645-56. doi: 10.1172/JCI46274