Bio-Connect

InVivoMAb anti-mouse TIM-3 (CD366)

BE0275
Bio X Cell
ApplicationsFlow Cytometry, Neutralisation/Blocking
Product group Antibodies
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-mouse TIM-3 (CD366)
  • Delivery Days Customer
    7
  • Applications
    Flow Cytometry, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    B8.2C12
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Rat
  • Isotype
    IgG1
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Hsu JM, Xia W, Hsu YH, et al. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 2018,9(1):1908. doi: 10.1038/s41467-018-04313-6
    Read this paper
  • Wang HW, Zhu XL, Qin LM, et al. Microglia activity modulated by T cell Ig and mucin domain protein 3 (Tim-3). Cell Immunol. 2015,293(1):49-58. doi: 10.1016/j.cellimm.2014.12.005
    Read this paper
  • Hou H, Liu W, Wu S, et al. Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock. PLoS One. 2014,9(10):e110585. doi: 10.1371/journal.pone.0110585
    Read this paper
  • Hongo D, Tang X, Baker J, et al. Requirement for interactions of natural killer T cells and myeloid-derived suppressor cells for transplantation tolerance. Am J Transplant. 2014,14(11):2467-77. doi: 10.1111/ajt.12914
    Read this paper
  • Chabtini L, Mfarrej B, Mounayar M, et al. TIM-3 regulates innate immune cells to induce fetomaternal tolerance. J Immunol. 2013,190(1):88-96. doi: 10.4049/jimmunol.1202176
    Read this paper
  • Hongo D, Tang X, Dutt S, et al. Interactions between NKT cells and Tregs are required for tolerance to combined bone marrow and organ transplants. Blood. 2012,119(6):1581-9. doi: 10.1182/blood-2011-08-371948
    Read this paper
  • Wang F, Wan L, Zhang C, et al. Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells. Immunobiology. 2009,214(5):342-9. doi: 10.1016/j.imbio.2008.10.007
    Read this paper
  • Nakae S, Iikura M, Suto H, et al. TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells. Blood. 2007,110(7):2565-8.
    Read this paper
  • Frisancho-Kiss S, Nyland JF, Davis SE, et al. Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity. J Immunol. 2006,176(11):6411-5.
    Read this paper
  • Monney L, Sabatos CA, Gaglia JL, et al. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature. 2002,415(6871):536-41.
    Read this paper