InVivoPlus anti-mouse GITR

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Bartkowiak T, Singh S, Yang G, et al. Unique potential of 4-1BB agonist antibody to promote durable regression of HPV+ tumors when combined with an E6/E7 peptide vaccine. Proc Natl Acad Sci U S A. 2015,112(38):E5290-9. doi: 10.1073/pnas.1514418112

Lu L, Xu X, Zhang B, et al. Combined PD-1 blockade and GITR triggering induce a potent antitumor immunity in murine cancer models and synergizes with chemotherapeutic drugs. J Transl Med. 2014,12:36. doi: 10.1186/1479-5876-12-36

Bulliard Y, Jolicoeur R, Windman M, et al. Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies. J Exp Med. 2013,210(9):1685-93. doi: 10.1084/jem.20130573

Côté AL, Zhang P, O'Sullivan JA, et al. Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens. J Immunol. 2011,186(1):275-83. doi: 10.4049/jimmunol.1001308

Johanns TM, Ertelt JM, Rowe JH, et al. Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection. PLoS Pathog. 2010,6(8):e1001043. doi: 10.1371/journal.ppat.1001043