RecombiMAb anti-mouse GITR

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Bartkowiak T, Singh S, Yang G, et al. Unique potential of 4-1BB agonist antibody to promote durable regression of HPV+ tumors when combined with an E6/E7 peptide vaccine. Proc Natl Acad Sci U S A. 2015,112(38):E5290-9. doi: 10.1073/pnas.1514418112

Lu L, Xu X, Zhang B, et al. Combined PD-1 blockade and GITR triggering induce a potent antitumor immunity in murine cancer models and synergizes with chemotherapeutic drugs. J Transl Med. 2014,12:36. doi: 10.1186/1479-5876-12-36

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Ronchetti S, Nocentini G, Petrillo MG, et al. CD8+ T cells: GITR matters. ScientificWorldJournal. 2012,2012:308265. doi: 10.1100/2012/308265

Kanamaru F, Youngnak P, Hashiguchi M, et al. Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells. J Immunol. 2004,172(12):7306-14.

Shimizu J, Yamazaki S, Takahashi T, et al. Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol. 2002,3(2):135-42.