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Western Blot analysis of Hela cell using IPO7 Polyclonal Antibody at dilution of 1:300
Western Blot analysis of Hela cell using IPO7 Polyclonal Antibody at dilution of 1:300
Western Blot analysis of Hela cell using IPO7 Polyclonal Antibody at dilution of 1:300

IPO7 Polyclonal Antibody

E-AB-16521
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    IPO7 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.5mg/ml
  • Scientific Description
    The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Rans GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
  • UNSPSC
    12352203