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IRE1 alpha (phospho Ser724) antibody

Name: IRE1 alpha (phospho Ser724) antibody
SKU: GTX132808_G10
Availability: BackOrder

GTX132808

ApplicationsWestern Blot

Product group Antibodies

TargetERN1

Overview

Supplier
GeneTex
Product Name
IRE1 alpha (phospho Ser724) antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.5 mg/ml
Conjugate
Unconjugated
Gene ID2081
Target name
ERN1
Target description
endoplasmic reticulum to nucleus signaling 1
Target synonyms
ER to nucleus signalling 1; hIRE1p; inositol-requiring 1; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; ire1-alpha; IRE1P; protein kinase/endoribonuclease; serine/threonine-protein kinase/endoribonuclease IRE1
Host
Rabbit
Isotype
IgG
Protein IDO75460
Protein Name
Serine/threonine-protein kinase/endoribonuclease IRE1
Scientific Description
The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Establishment of a novel ER-stress induced myopia model in mice.
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Bisphenol A exposure triggers endoplasmic reticulum stress pathway leading to ocular axial elongation in mice.
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Scleral PERK and ATF6 as targets of myopic axial elongation of mouse eyes.
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PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis.
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The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1alpha/XBP1s pathway. Yu W et al., 2022 May, Acta Pharm Sin B
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L-Ascorbic Acid Inhibits Breast Cancer Growth by Inducing IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Accumulation in the Nucleus. Choi YK et al., 2020 May 8, Nutrients
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Naphthoquinone derivative PPE8 induces endoplasmic reticulum stress in p53 null H1299 cells. Lien JC et al., 2015, Oxid Med Cell Longev
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