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ProductsBack/IRE1 alpha (phospho Ser724) antibody

IRE1 alpha (phospho Ser724) antibody

GTX132808
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetERN1
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Overview

  • Supplier
    GeneTex
  • Product Name
    IRE1 alpha (phospho Ser724) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2081
  • Target name
    ERN1
  • Target description
    endoplasmic reticulum to nucleus signaling 1
  • Target synonyms
    IRE1, IRE1P, IRE1a, hIRE1p, serine/threonine-protein kinase/endoribonuclease IRE1, ER to nucleus signalling 1, inositol-requiring 1, inositol-requiring enzyme 1, inositol-requiring protein 1, ire1-alpha, protein kinase/endoribonuclease
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75460
  • Protein Name
    Serine/threonine-protein kinase/endoribonuclease IRE1
  • Scientific Description
    The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Kang L, Ikeda SI, Yang Y, et al. Establishment of a novel ER-stress induced myopia model in mice. Eye Vis (Lond). 2023,10(1):44. doi: 10.1186/s40662-023-00361-2
    Read this paper
  • Chen J, Ikeda SI, Kang L, et al. Bisphenol A exposure triggers endoplasmic reticulum stress pathway leading to ocular axial elongation in mice. Front Med (Lausanne). 2023,10:1255121. doi: 10.3389/fmed.2023.1255121
    Read this paper
  • Ikeda SI, Kurihara T, Jiang X, et al. Scleral PERK and ATF6 as targets of myopic axial elongation of mouse eyes. Nat Commun. 2022,13(1):5859. doi: 10.1038/s41467-022-33605-1
    Read this paper
  • Tao J, Yin L, Wu A, et al. PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis. Front Oncol. 2022,12:836087. doi: 10.3389/fonc.2022.836087
    Read this paper
  • Yu W, Xu G, Chen H, et al. The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway. Acta Pharm Sin B. 2022,12(5):2315-2329. doi: 10.1016/j.apsb.2021.12.025
    Read this paper
  • Choi YK, Kang JI, Han S, et al. L-Ascorbic Acid Inhibits Breast Cancer Growth by Inducing IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Accumulation in the Nucleus. Nutrients. 2020,12(5). doi: 10.3390/nu12051351
    Read this paper
  • Lien JC, Huang CC, Lu TJ, et al. Naphthoquinone derivative PPE8 induces endoplasmic reticulum stress in p53 null H1299 cells. Oxid Med Cell Longev. 2015,2015:453679. doi: 10.1155/2015/453679
    Read this paper

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