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ProductsBack/IRE1 alpha (phospho Ser724) antibody

IRE1 alpha (phospho Ser724) antibody

GTX132808
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetERN1
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Overview

  • Supplier
    GeneTex
  • Product Name
    IRE1 alpha (phospho Ser724) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2081
  • Target name
    ERN1
  • Target description
    endoplasmic reticulum to nucleus signaling 1
  • Target synonyms
    ER to nucleus signalling 1; hIRE1p; inositol-requiring 1; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; ire1-alpha; IRE1P; protein kinase/endoribonuclease; serine/threonine-protein kinase/endoribonuclease IRE1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75460
  • Protein Name
    Serine/threonine-protein kinase/endoribonuclease IRE1
  • Scientific Description
    The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Establishment of a novel ER-stress induced myopia model in mice.
    Read more
  • Bisphenol A exposure triggers endoplasmic reticulum stress pathway leading to ocular axial elongation in mice.
    Read more
  • Scleral PERK and ATF6 as targets of myopic axial elongation of mouse eyes.
    Read more
  • PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis.
    Read more
  • The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1alpha/XBP1s pathway. Yu W et al., 2022 May, Acta Pharm Sin B
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  • L-Ascorbic Acid Inhibits Breast Cancer Growth by Inducing IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Accumulation in the Nucleus. Choi YK et al., 2020 May 8, Nutrients
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  • Naphthoquinone derivative PPE8 induces endoplasmic reticulum stress in p53 null H1299 cells. Lien JC et al., 2015, Oxid Med Cell Longev
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