Western Blot Positive WB detected in: Mouse liver tissue All lanes: IRF9 antibody at 3ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 44 kDa Observed band size: 44 kDa
IRF9 Antibody
CSB-PA011824LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetIRF9
Overview
- SupplierCusabio
- Product NameIRF9 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10379
- Target nameIRF9
- Target descriptioninterferon regulatory factor 9
- Target synonymsIFN-alpha-responsive transcription factor subunit; interferon regulatory factor 9; interferon-stimulated gene factor 3 gamma; interferon-stimulated transcription factor 3, gamma (48kD); interferon-stimulated transcription factor 3, gamma 48kDa; IRF-9; ISGF3; ISGF-3 gamma; ISGF3 p48 subunit; ISGF3G; p48; transcriptional regulator ISGF3 subunit gamma
- HostRabbit
- IsotypeIgG
- Scientific DescriptionTranscription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203