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IHC-P analysis of human brain tissue using GTX55343 ITCH (phospho Tyr420) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
IHC-P analysis of human brain tissue using GTX55343 ITCH (phospho Tyr420) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
IHC-P analysis of human brain tissue using GTX55343 ITCH (phospho Tyr420) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide

ITCH (phospho Tyr420) antibody

GTX55343
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetITCH
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Overview

  • Supplier
    GeneTex
  • Product Name
    ITCH (phospho Tyr420) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID83737
  • Target name
    ITCH
  • Target description
    itchy E3 ubiquitin protein ligase
  • Target synonyms
    ADMFD; AIF4; AIP4; atrophin-1 interacting protein 4; E3 ubiquitin-protein ligase Itchy homolog; HECT-type E3 ubiquitin transferase Itchy homolog; itchy E3 ubiquitin protein ligase homolog; NAPP1; NFE2-associated polypeptide 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96J02
  • Protein Name
    E3 ubiquitin-protein ligase Itchy homolog
  • Scientific Description
    This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

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