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ProductsBack/Ivosidenib [1448347-49-6]
Ivosidenib [1448347-49-6]

Ivosidenib [1448347-49-6]

Research Use Only
T3617
TargetMol Chemicals
CAS Number1448347-49-6
DownloadMSDS
Product group Chemicals
Estimated Purity99.60%
Molecular Weight582.96
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Ivosidenib [1448347-49-6]
  • Delivery Days Customer
    4
  • CAS Number
    1448347-49-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Ivosidenib
  • Estimated Purity
    99.60%
  • Molecular Formula
    C28H22ClF3N6O3
  • Molecular Weight
    582.96
  • Scientific Description
    Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity. It specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of the oncometabolite 2-hydroxyglutarate (2 hG), which may induce cellular differentiation and inhibit cellular proliferation in IDH1-expressing tumor cells.
  • Shelf life instruction
    3 years
  • SMILES
    Fc1cncc(c1)N([C@H](C(=O)NC1CC(F)(F)C1)c1ccccc1Cl)C(=O)[C@@H]1CCC(=O)N1c1cc(ccn1)C#N
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200