Ixazomib

MedChem Express

Ixazomib [1072833-77-2]

5

1072833-77-2

Research Use Only

99.85

C14H19BCl2N2O4

361.03

Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (beta5) site of the 20S proteasome with an IC 50 of 3.4 nM ( K i of 0.93 nM).

OB([C@@H](NC(CNC(C1=CC(Cl)=CC=C1Cl)=O)=O)CC(C)C)O

-20°C,2°C to 8°C

12352200