Ixazomib [1072833-77-2]
T2122
CAS Number1072833-77-2
Product group Chemicals
Estimated Purity98.07%
Molecular Weight361.03
Overview
- SupplierTargetMol Chemicals
- Product NameIxazomib [1072833-77-2]
- Delivery Days Customer4
- CAS Number1072833-77-2
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameIxazomib
- Estimated Purity98.07%
- Molecular FormulaC14H19BCl2N2O4
- Molecular Weight361.03
- Scientific DescriptionIxazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (beta5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (beta1) and trypsin-like (beta2) proteolytic sites (IC50: 31/3500 nM).
- Shelf life instruction3 years
- SMILESCC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B(O)O
- Storage Instruction-20°C
- UNSPSC12352200
References
- Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer. Kupperman E et al., 2010 Mar 1, Cancer ResRead more
Related products
Product group Chemicals
IxazomibORB1306436
CAS Number1072833-77-2
Estimated Purity98.07%
Molecular Weight361.03
- SizePrice
Product group Chemicals
IxazomibHY-10453
CAS Number1072833-77-2
Estimated Purity99.85
Molecular Weight361.03
- SizePrice
Product group Chemicals
MLN2238M2285
CAS Number1072833-77-2
Estimated Purity>99%
Molecular Weight361.03
- SizePrice
Product group Chemicals
Ixazomib [MLN2238]AG-CR1-3670
CAS Number1072833-77-2
Estimated Purity>98%
Molecular Weight361
- SizePrice
