![J-113863 [353791-85-2] J-113863 [353791-85-2]](https://www.targetmol.com/group3/M00/02/7C/CgoaEGY7NMuEHma8AAAAAPOZr8w590.png)
J-113863 [353791-85-2]
T11699
Overview
- SupplierTargetMol Chemicals
- Product NameJ-113863 [353791-85-2]
- Delivery Days Customer4
- CAS Number353791-85-2
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameJ-113863
- Molecular FormulaC30H37Cl2IN2O2
- Molecular Weight655.44
- Scientific DescriptionJ-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-alpha receptors. Anti-inflammatory effect. J-113863 is a potent and selective CCR1 (CD18) antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively.
- Shelf life instruction3 years
- SMILES[I-].CC[N+]1(C\C2=C\CCCCCC2)CCC(CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12
- Storage Instruction-20°C
- UNSPSC12352200