Jagged 1 antibody [4A24]
GTX52879
ApplicationsFlow Cytometry, Western Blot, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetJAG1
Overview
- SupplierGeneTex
- Product NameJagged 1 antibody [4A24]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. FACS: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4A24
- Concentration500 ug/ml
- ConjugateUnconjugated
- Gene ID182
- Target nameJAG1
- Target descriptionjagged canonical Notch ligand 1
- Target synonymsAGS; AGS1; AHD; AWS; CD339; DCHE; HJ1; JAGL1; protein jagged-1
- HostMouse
- IsotypeIgG2
- Protein IDP78504
- Protein NameProtein jagged-1
- Scientific DescriptionThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Acute Lymphoblastic Leukemia Cells Inhibit the Differentiation of Bone Mesenchymal Stem Cells into Osteoblasts In Vitro by Activating Notch Signaling. Yang GC et al., 2015, Stem Cells IntRead more