Immunohistochemical staining of human cervical cancer tissue (40X magnification) using GeneTex's Protein A purified anti-Jagged-1 antibody. Tissue was fixed with formalin and embedded in paraffin. Hematoxylin was used to counter-stain cells. A 1:100 dilution of primary antibody was used.
Immunohistochemical staining of human cervical cancer tissue (40X magnification) using GeneTex's Protein A purified anti-Jagged-1 antibody. Tissue was fixed with formalin and embedded in paraffin. Hematoxylin was used to counter-stain cells. A 1:100 dilution of primary antibody was used.
Jagged 1 antibody
GTX48691
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetJAG1
Overview
- SupplierGeneTex
- Product NameJagged 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. ICC/IF: 1:200-1:1000. IHC-P: 1:100-1:500. ELISA: 1:20000-1:100000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.15 mg/ml
- ConjugateUnconjugated
- Gene ID182
- Target nameJAG1
- Target descriptionjagged canonical Notch ligand 1
- Target synonymsAGS, AGS1, AHD, AWS, CD339, CMT2HH, DCHE, HJ1, JAGL1, protein jagged-1
- HostRabbit
- IsotypeIgG
- Protein IDP78504
- Protein NameProtein jagged-1
- Scientific DescriptionThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoies
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
References
- Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment. Zhu Q et al., 2020 Feb 11, Biol ResRead this paper
- Linc-OIP5 loss regulates migration and invasion in MDA-MB-231 breast cancer cells by inhibiting YAP1/JAG1 signaling. Zhu Q et al., 2020 Jan, Oncol LettRead this paper
Datasheet
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