Immunofluorescence Microscopy using GeneTexs Protein A purified anti-Jagged-1 antibody of human corneal epithelial cells. Primary antibody was used at a 1:500 dilution. The Jagged1 Green staining) is localized to the cytoplasm and is consistent with reports in the literature. The nucleus is stained with Bis benzimide (blue)
Immunofluorescence Microscopy using GeneTexs Protein A purified anti-Jagged-1 antibody of human corneal epithelial cells. Primary antibody was used at a 1:500 dilution. The Jagged1 Green staining) is localized to the cytoplasm and is consistent with reports in the literature. The nucleus is stained with Bis benzimide (blue)
Jagged 1 antibody
GTX48691
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetJAG1
Overview
- SupplierGeneTex
- Product NameJagged 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. ICC/IF: 1:200-1:1000. IHC-P: 1:100-1:500. ELISA: 1:20000-1:100000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.15 mg/ml
- ConjugateUnconjugated
- Gene ID182
- Target nameJAG1
- Target descriptionjagged canonical Notch ligand 1
- Target synonymsAGS, AGS1, AHD, AWS, CD339, CMT2HH, DCHE, HJ1, JAGL1, protein jagged-1
- HostRabbit
- IsotypeIgG
- Protein IDP78504
- Protein NameProtein jagged-1
- Scientific DescriptionThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoies
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Zhu Q, Li J, Wu Q, et al. Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment. Biol Res. 2020,53(1):5. doi: 10.1186/s40659-020-0273-0Read this paper
- Zhu Q, Li Y, Dong X, et al. Linc-OIP5 loss regulates migration and invasion in MDA-MB-231 breast cancer cells by inhibiting YAP1/JAG1 signaling. Oncol Lett. 2020,19(1):103-112. doi: 10.3892/ol.2019.11071Read this paper
Datasheet
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