JAK3 covalent inhibitor-1 [2300106-50-5]

TargetMol Chemicals

JAK3 covalent inhibitor-1 [2300106-50-5]

114

2300106-50-5

Research Use Only

JAK3 covalent inhibitor-1

C22H17FN6O2S

448.47

JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus kinase 3 (JAK3), possessing an IC50 of 11 nM and demonstrating a 246-fold selectivity compared to other JAKs.

3 years

N(C#N)[C@@H]1C=2C([C@H](NS(=O)(=O)C3=CC(F)=CC=C3)C1)=CC=C(C2)C4=C5C(=NC=N4)NC=C5

-20°C

51202000