JC-10

Chemodex

JC-10

10

Research Use Only

>98%

C25H29Cl2IN4

583.3

Chemical. CAS: n.a. Synthetic Derivative of JC-1 useful for determining mitochondrial membrane potential by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. Accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (570 nm) in healthy cells. Upon cell injury, as membrane potential decreases, JC-10 monomers are generated, resulting in a shift to green emission (520 nm). Shows improved solubility compared to JC-1 in aqueous media and an ability to detect subtler changes in mitochondrial membrane potential loss. Spectral data: lambdaex 510 nm - lambdaem 525. - Derivative of JC-1 useful for determining mitochondrial membrane potential by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. Accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (570 nm) in healthy cells. Upon cell injury, as membrane potential decreases, JC-10 monomers are generated, resulting in a shift to green emission (520 nm). Shows improved solubility compared to JC-1 in aqueous media and an ability to detect subtler changes in mitochondrial membrane potential loss. Spectral data: lambdaex 510 nm - lambdaem 525.

CCN(C1=CC=C(Cl)C=C1N/2CC)C2=C\C=C\C3=[N+](CC)C(C=CC(Cl)=C4)=C4N3CC.[I-]

-20°C,2°C to 8°C

12162000