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JKE-1674 [2421119-60-8]

JKE-1674 [2421119-60-8]

T37314
TargetMol Chemicals
CAS Number2421119-60-8
Product group Chemicals
Molecular Weight451.3
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    JKE-1674 [2421119-60-8]
  • Delivery Days Customer
    9
  • CAS Number
    2421119-60-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    JKE-1674
  • Molecular Formula
    C20H20Cl2N4O4
  • Molecular Weight
    451.3
  • Scientific Description
    JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210, which is converted to butyronitrile oxide JKE-1777. JKE-1674 kills LOX-IMVI cells in the same manner as ML-210 and is completely rescued by ferroptosis inhibitors.
  • Shelf life instruction
    3 years
  • SMILES
    O\N=C(/C[N+]([O-])=O)C(=O)N1CCN(CC1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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