JNJ-63576253

MedChem Express

JNJ-63576253 [2110428-64-1]

10

2110428-64-1

Research Use Only

99.22

C23H22ClF3N6O2S

538.97

JNJ-63576253 (TRC-253) is a potent and orally active full antagonist of androgen receptor (AR) , with IC 50 s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC) [1] .

[H]Cl.O=C(N(C(N1C2=CC=C(N=C2)OC3CCNCC3)=S)C(C=C4C(F)(F)F)=CN=C4C#N)C51CCC5

2°C to 8°C

12352200