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JNJ-63576253 free base [2110426-27-0]

JNJ-63576253 free base [2110426-27-0]

T8933
TargetMol Chemicals
CAS Number2110426-27-0
Product group Chemicals
Estimated Purity98.32%
Molecular Weight502.51
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    JNJ-63576253 free base
  • Delivery Days Customer
    4
  • CAS Number
    2110426-27-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    JNJ-63576253 free base
  • Estimated Purity
    98.32%
  • Molecular Formula
    C23H21F3N6O2S
  • Molecular Weight
    502.51
  • Scientific Description
    JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC).
  • Shelf life instruction
    3 years
  • SMILES
    FC(F)(F)c1cc(cnc1C#N)N1C(=S)N(c2ccc(OC3CCNCC3)nc2)C2(CCC2)C1=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200