Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Catenin-gamma antibody.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Catenin-gamma antibody.
JUP Antibody
CSB-PA846873
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetJUP
Overview
- SupplierCusabio
- Product NameJUP Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3728
- Target nameJUP
- Target descriptionjunction plakoglobin
- Target synonymscatenin (cadherin-associated protein), gamma 80kDa; CTNNG; desmoplakin III; desmoplakin-3; desmosomal protein 3; DP3; DPIII; junction plakoglobin; PDGB; PG; PKGB
- HostRabbit
- IsotypeIgG
- Protein IDP14923
- Protein NameJunction plakoglobin
- Scientific DescriptionCommon junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton By similarity. T Naka, J. Clin. Pathol., Dec 2001; 54: 945 - 950. AR Burns, J. Immunol., Sep 1997; 159: 2893. Frank T. Kolligs, Genes & Dev., Jun 2000; 14: 1319. Jon A. Ukropec, J. Biol. Chem., Feb 2000; 275: 5983.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203