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Western blot analysis of extracts from HT-29, MCF-7 and C2C12 cells using g-Catenin Antibody.
Western blot analysis of extracts from HT-29, MCF-7 and C2C12 cells using g-Catenin Antibody.
Western blot analysis of extracts from HT-29, MCF-7 and C2C12 cells using g-Catenin Antibody.

JUP Antibody

CSB-PA909861
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Rat
TargetJUP
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Overview

  • Supplier
    Cusabio
  • Product Name
    JUP Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID3728
  • Target name
    JUP
  • Target description
    junction plakoglobin
  • Target synonyms
    catenin (cadherin-associated protein), gamma 80kDa; CTNNG; desmoplakin III; desmoplakin-3; desmosomal protein 3; DP3; DPIII; junction plakoglobin; PDGB; PG; PKGB
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP14923
  • Protein Name
    Junction plakoglobin
  • Scientific Description
    Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton Characterization of the interactions of a-catenin with a-actinin and beta-catenin/plakoglobin. Nieset J.E., Redfield A.R., Jin F., et al. J. Cell Sci. 110:1013-1022(1997) Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion. Yamamoto M., Bharti A., Li Y., Kufe D. J. Biol. Chem. 272:12492-12494(1997) The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn). Holsinger L.J., Ward K., Duffield B., Zachwieja J., Jallal B. Oncogene 21:7067-7076(2002)
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203