JUP Antibody, FITC conjugated
CSB-PA12839C0RB
ReactivityHuman
Product group Antibodies
TargetJUP
Overview
- SupplierCusabio
- Product NameJUP Antibody, FITC conjugated
- Delivery Days Customer20
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateFITC
- Gene ID3728
- Target nameJUP
- Target descriptionjunction plakoglobin
- Target synonymscatenin (cadherin-associated protein), gamma 80kDa; CTNNG; desmoplakin III; desmoplakin-3; desmosomal protein 3; DP3; DPIII; junction plakoglobin; PDGB; PG; PKGB
- HostRabbit
- IsotypeIgG
- Protein IDP14923
- Protein NameJunction plakoglobin
- Scientific DescriptionCommon junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203