Bio-Connect

JUP Antibody, FITC conjugated

CSB-PA12839C0RB
Cusabio
ReactivityHuman
Product group Antibodies
TargetJUP
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Overview

  • Supplier
    Cusabio
  • Product Name
    JUP Antibody, FITC conjugated
  • Delivery Days Customer
    20
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    FITC
  • Gene ID3728
  • Target name
    JUP
  • Target description
    junction plakoglobin
  • Target synonyms
    catenin (cadherin-associated protein), gamma 80kDa; CTNNG; desmoplakin III; desmoplakin-3; desmosomal protein 3; DP3; DPIII; junction plakoglobin; PDGB; PG; PKGB
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP14923
  • Protein Name
    Junction plakoglobin
  • Scientific Description
    Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203