K-252c

MedChem Express

K-252c [85753-43-1]

10

85753-43-1

Research Use Only

99.0

C20H13N3O

311.34

K-252c, a staurosporine analog isolated from Nocardiopsis sp., is a cell-permeable PKC inhibitor, with an IC50 of 2.45 microM. K-252c induces apoptosis in human chronic myelogenous leukemia cancer cells. K-252c also inhibits beta-lactamase, chymotrypsin, and malate dehydrogenase[1][2][3].

O=C1NCC2=C1C3=C(C4=C2C5=C(N4)C=CC=C5)NC6=C3C=CC=C6

-20°C

12352200