Kallikrein 7 antibody [5J28]

GeneTex

Kallikrein 7 antibody [5J28]

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, Neutralisation/Blocking

Research Use Only

Monoclonal

5J28

500 ug/ml

Unconjugated

KLK7

kallikrein related peptidase 7

hK7; kallikrein 7 (chymotryptic, stratum corneum); kallikrein-7; PRSS6; SCCE; serine protease 6; signal protein; stratum corneum chymotryptic enzyme

Mouse

IgG2

Kallikrein-7

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]

Human

-20°C or -80°C,2°C to 8°C

12352203