Kallikrein 7 antibody [5J28]
GTX52888
ApplicationsWestern Blot, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameKallikrein 7 antibody [5J28]
- Delivery Days Customer10
- ApplicationsWestern Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5J28
- Concentration500 ug/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203