Western Blot Positive WB detected in: MCF-7 whole cell lysate All lanes: KARS antibody at 2.5microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 69, 72 kDa Observed band size: 69 kDa

KARS Antibody

Name: KARS Antibody
SKU: CSB-PA04689A0RB_C90
Availability: BackOrder

CSB-PA04689A0RB

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetKARS1

Overview

Supplier
Cusabio
Product Name
KARS Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID3735
Target name
KARS1
Target description
lysyl-tRNA synthetase 1
Target synonyms
CMTRIB; DEAPLE; DFNB89; KARS; KARS2; KRS; LEPID; lysine tRNA ligase; lysine--tRNA ligase; lysRS
Host
Rabbit
Isotype
IgG
Protein IDQ15046
Protein Name
Lysine--tRNA ligase
Scientific Description
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:9278442, PubMed:18029264, PubMed:18272479). When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages (PubMed:15851690). Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity (PubMed:5338216, PubMed:14975237, PubMed:19524539, PubMed:23159739). (Microbial infection) Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

KARS Antibody

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