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Lysyl-tRNA synthetase antibody

GTX102113
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetKARS1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Lysyl-tRNA synthetase antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3735
  • Target name
    KARS1
  • Target description
    lysyl-tRNA synthetase 1
  • Target synonyms
    CMTRIB; DEAPLE; DFNB89; KARS; KARS2; KRS; LEPID; lysine tRNA ligase; lysine--tRNA ligase; lysRS
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15046
  • Protein Name
    Lysine--tRNA ligase
  • Scientific Description
    Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • MHC class I and II peptide homology regulates the cellular immune response. Halpert MM et al., 2020 Jun, FASEB J
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