KCNN2 antibody, Internal

GeneTex

KCNN2 antibody, Internal

7

This antibody is expected to recognize both isoforms (NP_067627.2; NP_740721.1).

WB: 0.3-1microg/ml. IHC-P: 1-2microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

KCNN2

potassium calcium-activated channel subfamily N member 2

apamin-sensitive small-conductance Ca2+-activated potassium channel; hSK2; KCa2.2; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; SK2; SKCa 2; SKCA2; small conductance calcium-activated potassium channel 2; small conductance calcium-activated potassium channel protein 2

Goat

IgG

Small conductance calcium-activated potassium channel protein 2

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Human

-20°C or -80°C,2°C to 8°C

12352203