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CgoaEGY7Ol2EU6reAAAAAGe3YUc583.png
KDM5A-IN-1 [1905481-36-8]
T15650
Overview
- SupplierTargetMol Chemicals
- Product NameKDM5A-IN-1 [1905481-36-8]
- Delivery Days Customer9
- CAS Number1905481-36-8
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameKDM5A-IN-1
- Molecular FormulaC15H22N4O2
- Molecular Weight290.36
- Scientific DescriptionKDM5A-IN-1 is an orally available, potent and selective inhibitor of the pan-histidine lysine demethylase 5 KDM5, inhibiting KDM5A, KDM5B, and KDM5C with IC50 values of 45 nM, 56 nM, and 55 nM, respectively.KDM5A-IN-1 inhibits PC9 H3K4Me3, and may be useful in cancer research.
- Shelf life instruction3 years
- SMILESCC(C)c1cc([nH]n1)C(=O)N1CC[C@H](C1)NC(=O)C1CC1
- Storage Instruction-20°C
- UNSPSC51202000
References
- Liang J, et al. From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors. Bioorg Med Chem Lett. 2017 Jul 1;27(13):2974-2981.Read more