
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA176057(KDM5B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
KDM5B Antibody
CSB-PA176057
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetKDM5B
Overview
- SupplierCusabio
- Product NameKDM5B Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10765
- Target nameKDM5B
- Target descriptionlysine demethylase 5B
- Target synonymsCT31, JARID1B, MRT65, PLU-1, PLU1, PPP1R98, PUT1, RBBP2H1A, RBP2-H1, lysine-specific demethylase 5B, [histone H3]-trimethyl-L-lysine(4) demethylase 5B, cancer/testis antigen 31, histone demethylase JARID1B, jumonji, AT rich interactive domain 1B, jumonji/ARID domain-containing protein 1B, lysine (K)-specific demethylase 5B, protein phosphatase 1, regulatory subunit 98, putative DNA/chromatin binding motif, retinoblastoma-binding protein 2 homolog 1, retinoblastoma-binding protein 2, homolog 1A
- HostRabbit
- IsotypeIgG
- Protein IDQ9UGL1
- Protein NameLysine-specific demethylase 5B
- Scientific DescriptionPLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161







