
IHC-P analysis of rat brain tissue using GTX60284 KDM5B antibody. Dilution : 1:200
KDM5B antibody
GTX60284
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetKDM5B
Overview
- SupplierGeneTex
- Product NameKDM5B antibody
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:50-400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10765
- Target nameKDM5B
- Target descriptionlysine demethylase 5B
- Target synonyms[histone H3]-trimethyl-L-lysine(4) demethylase 5B; cancer/testis antigen 31; CT31; histone demethylase JARID1B; JARID1B; jumonji, AT rich interactive domain 1B; jumonji/ARID domain-containing protein 1B; lysine (K)-specific demethylase 5B; lysine-specific demethylase 5B; MRT65; PLU1; PLU-1; PPP1R98; protein phosphatase 1, regulatory subunit 98; PUT1; putative DNA/chromatin binding motif; RBBP2H1A; RBP2-H1; retinoblastoma-binding protein 2 homolog 1; retinoblastoma-binding protein 2, homolog 1A
- HostRabbit
- IsotypeIgG
- Protein IDQ9UGL1
- Protein NameLysine-specific demethylase 5B
- Scientific DescriptionThis gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing resultsi n multiple transcript variants. [provided by RefSeq, Sep 2015]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Overcoming radio-resistance in esophageal squamous cell carcinoma via hypermethylation of PIK3C3 promoter region mediated by KDM5B loss. Wang X et al., 2022 May 18, J Radiat ResRead more