Kendomycin [183202-73-5]

BioViotica

Kendomycin [183202-73-5]

10

183202-73-5

Research Use Only

>98%

Warning

C29H42O6

486.6

Antibiotic. Potent endothelin receptor antagonist. Anti-osteoporotic. Antibacterial. Anticancer agent. Cytotoxic against several carcinoma cell lines (GI50<100nM). 20S proteasome inhibitor. Induces apoptosis by inhibition of chymotrypsin-like proteasome activity. - Chemical. CAS: 183202-73-5. Formula: C29H42O6. MW: 486.6. Isolated from Streptomyces violaceoruber. Antibiotic. Potent endothelin receptor antagonist. Anti-osteoporotic. Antibacterial. Cytotoxic. Mediates its cytotoxic effects, at least in part, through proteasome inhibition.

[H][C@]12CC[C@H](C)\C=C(C)\C[C@@H](C)C[C@H](C)[C@]3(O)OC4=C(C)C(=O)C(O)=C(C4=C3)[C@]([H])(O1)[C@H](C)[C@@H](O)[C@H]2C

-20°C,2°C to 8°C

12352200