Kendomycin

MedChem Express

Kendomycin [183202-73-5]

10

183202-73-5

Research Use Only

98.00

C29H42O6

486.64

Kendomycin ((-)-TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 microg/mL). Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent[1][2].

OC(C1=O)=C([C@]([C@@H]([C@H]2O)C)([H])O[C@@](CC[C@@H]3C)([H])[C@@H]2C)C(C(O4)=C1C)=C[C@@]4([C@H](C[C@@H](C/C(C)=C/3)C)C)O

-20°C

12352200