
This picture was kindly supplied as part of the review submitted by Dr Robert ODonogue. Tissue sections from mouse lung were stained with GTX20833 at a dilution of 1/50.
Ki67 antibody
GTX20833
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMKI67
Overview
- SupplierGeneTex
- Product NameKi67 antibody
- Delivery Days Customer9
- Application Supplier NoteFor IHC-P: Use at a concentration of 1 0 - 2 0 microg / m l f o r 3 0 m i n a t R T. Staining of formalin/paraffin tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4288
- Target nameMKI67
- Target descriptionmarker of proliferation Ki-67
- Target synonymsKIA, MIB-, MIB-1, PPP1R105, proliferation marker protein Ki-67, Molecular Immunology Borstel antibody 1, antigen Ki67, antigen identified by monoclonal antibody Ki-67, proliferation-related Ki-67 antigen, protein phosphatase 1, regulatory subunit 105
- HostRabbit
- IsotypeIgG
- Protein IDP46013
- Protein NameProliferation marker protein Ki-67
- Scientific DescriptionThis gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
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- Wu C, Wang M, Shi H. Cholesterol Promotes Colorectal Cancer Growth by Activating the PI3K/AKT Pathway. J Oncol. 2022,2022:1515416. doi: 10.1155/2022/1515416Read this paper
- Xu X, Tassone B, Ostano P, et al. HSD17B7 gene in self-renewal and oncogenicity of keratinocytes from Black versus White populations. EMBO Mol Med. 2021,13(7):e14133. doi: 10.15252/emmm.202114133Read this paper
- Markezana A, Goldberg SN, Kumar G, et al. Incomplete thermal ablation of tumors promotes increased tumorigenesis. Int J Hyperthermia. 2021,38(1):263-272. doi: 10.1080/02656736.2021.1887942Read this paper
- Liu J, Hu HB, Liu YM, et al. LncRNA HOTTIP promotes the proliferation and invasion of ovarian cancer cells by activating the MEK/ERK pathway. Mol Med Rep. 2020,22(5):3667-3676. doi: 10.3892/mmr.2020.11452Read this paper
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- Li M, Zhang X, Lu Y, et al. The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines. Cell Death Dis. 2020,11(1):31. doi: 10.1038/s41419-020-2225-6Read this paper
- Bordignon P, Bottoni G, Xu X, et al. Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant. Cell Rep. 2019,28(9):2358-2372.e6. doi: 10.1016/j.celrep.2019.07.092Read this paper
- Chou CM, Chen YC, Su S, et al. Activation of MEK2 is sufficient to induce skin papilloma formation in transgenic zebrafish. J Biomed Sci. 2015,22:102. doi: 10.1186/s12929-015-0207-2Read this paper
- Trazzi S, Steger M, Mitrugno VM, et al. CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3beta/beta-catenin signaling. J Biol Chem. 2010,285(13):10098-10109. doi: 10.1074/jbc.M109.043711Read this paper






![FACS analysis of human peripheral blood mononuclear cells stimulated with PHA using GTX00538-08 Ki67 antibody [Ki-67] (PE).](https://www.genetex.com/upload/website/prouct_img/normal/GTX00538-08/GTX00538-08_20191025_AP_006_84_w_23053121_518.webp)
![ICC/IF analysis of U2OS cells using GTX00538 Ki67 antibody [Ki-67]. Green : Primary antibody Blue : DAPI](https://www.genetex.com/upload/website/prouct_img/normal/GTX00538/GTX00538_20191025_AP_002_83_w_23053121_446.webp)