KIF3A antibody

GeneTex

KIF3A antibody

9

WB: 1:2,000. IHC-P: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

KIF3A

kinesin family member 3A

FLA10; kinesin family protein 3A; kinesin-like protein KIF3A; KLP-20; microtubule plus end-directed kinesin motor 3A

Rabbit

IgG

Kinesin-like protein KIF3A

The kinesin superfamily (KIFs) of proteins consists of a class of microtubule-dependent motors that plays a major role in many cellular and developmental functions, including organelle transport, mitosis, meiosis, and possibly long-range signaling in neurons. The KIF proteins are primarily associated with anterograde transport of vesicles and organelles in neurons, epithelial cells, and melanosomes with bidirectional transport of mitochondria and mediating transport between the endoplasmic reticulum (ER) and the Golgi complex. KIF3 motor complex is composed of the KIF3A, KIF3B, and KIF3C motor subunits, that associate as heterodimers, in which KIF3B and KIF3C are alternative partners of KIF3A. KIF3A/B has been shown to function in vivo as a motor for the anterograde fast axonal transport of membranebound organelles in neurons. KIF3 plays a crucial role during development. KIF3A-/- and KIF3B-/- mice do not survive beyond midgestation.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203