Kira8 [1630086-20-2]

MedChem Express

Kira8 [1630086-20-2]

10

1630086-20-2

Research Use Only

98.90

C31H29ClN6O3S

601.12

Kira8 (AMG-18) is a mono-selective IRE1alpha inhibitor that allosterically attenuates IRE1alpha RNase activity with an IC50 of 5.9 nM[1].

O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(OC4=NC=CC=C4C5=NC(N[C@@H]6CNCCC6)=NC=C5)C3=CC=C2)=O

-20°C, 3 years; 4°C, 2 years (Powder)

12352200