Kira8 (Hydrochloride) [2250019-92-0]

MedChem Express

Kira8 (Hydrochloride) [2250019-92-0]

10

2250019-92-0

Research Use Only

C31H30Cl2N6O3S

637.58

Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1alpha inhibitor that allosterically attenuates IRE1alpha RNase activity with an IC50 of 5.9 nM[1].

O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(C3=CC=C2)OC4=NC=CC=C4C5=NC(N[C@H]6CNCCC6)=NC=C5)=O.[H]Cl

12352200