Kira8 Hydrochloride [2250019-92-0]
T11762
CAS Number2250019-92-0
Product group Chemicals
Molecular Weight637.58
Overview
- SupplierTargetMol Chemicals
- Product NameKira8 Hydrochloride [2250019-92-0]
- Delivery Days Customer10
- CAS Number2250019-92-0
- CertificationResearch Use Only
- Chemical NameKira8 Hydrochloride
- Molecular FormulaC31H30Cl2N6O3S
- Molecular Weight637.58
- Scientific DescriptionKira8 Hydrochloride is a mono-selective IRE1alpha inhibitor that allosterically attenuates IRE1alpha RNase activity with an IC50 of 5.9 nM.
- Shelf life instruction3 years
- SMILESCl.Cc1ccc2c(NS(=O)(=O)c3ccccc3Cl)cccc2c1Oc1ncccc1-c1ccnc(N[C@H]2CCCNC2)n1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Morita S, Villalta SA, Feldman HC, et al. Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes. Cell Metab. 2017,25(4):883-897.e8. doi: 10.1016/j.cmet.2017.03.018Read this paper
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