KL001

MedChem Express

KL001 [309928-48-1]

5

309928-48-1

Research Use Only

99.68

C21H22N2O4S

398.484

KL001 is a first-in-class cryptochrome ( CRY , a flavoproteins that are sensitive to blue light, and is involved in the circadian rhythms of plants and animals) stabilizer which specifically interacts with CRY1 and CRY2. KL001 prevents ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001 has the potential to control fasting hormone-induced gluconeogenesis [1] [2] [3] .

CS(=O)(N(CC(O)CN1C2=C(C3=C1C=CC=C3)C=CC=C2)CC4=CC=CO4)=O

-20°C

12352200